From The Maze Where Realities Converge
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Things that you do
- Aerobic exercise. The standard protocol of 40 minutes three times a week plus warm-up and cool-down should work. . This says after 16 weeks, 60-69% of patients no longer met diagnostic criteria for depression. Compared with antidepressants, this is a slower response, but relapse rate is lower, especially if they keep exercizing.
- Running versus weight lifting in the treatment of depression - found weights are just as effective.
- Read this book - It's not a book, it's a drug in word form. Studied many times and shown to be as good as therapy  Gains are maintained for years .
- Relaxation - like progressive muscle relaxation, EMG biofeedback, or autogenics. Lots of studies on this. Cochrane review concludes that it's effective, but less so than CBT
- Massage - Some self-reported improvements, but no intervention studies (p.4)
- Laughter yoga 
- Pranayama. Don't know if there are any studies specifically on this, but we do know that "for mind and body alike, there is no purgative like pranayama"
- Cold showers. Adapted cold shower as a potential treatment for depression is an intriguing proposal that brief cold stress is part of the evolutionary environment we are adapted to. "Exposure to cold is known to activate the sympathetic nervous system and increase the blood level of beta-endorphin and noradrenaline and to increase synaptic release of noradrenaline in the brain as well."
- Psychedelic therapy - http://www.beckleyfoundation.org/pdf/Psychedelic_Healing.pdf
Things that you nom
- Fish oils, 2-3g a day with EPA:DHA ratio of 3:1 or 4:1. Study published in Journal of Clinical Psychiatry with n of 432 found fish oil effective in depression without anxiety, less so in depression with anxiety. Meta-analysis of ten trials with n of 329 found strong effects.
- In theory, creatine supplementation could help depression, because the creatine-phosphate system is hypoactive in the brains of depressives. A preliminary study (no control group) showed improved symptoms in all eight subjects after 4 weeks. (And also found that creatine caused two manic-depressives to go manic). Half a gram (i.e. half a teaspoon) six times a day would probably do the trick, as it raises concentration of creatine-phosphate as much as the more conventional single 10-20g 
- St John's Wort. Here is a meta-analysis published in the BMJ with a total n of 1757 that found a strong effect, equivalent to antidepressants. This is a smaller meta-analysis showing a weaker, but still significant, effect.
- Placebo. About 75% as effective as antidepressant drugs. This says an active placebo (with side effects) is even more effective. Placebos work best when taken 4 times a day, and capsules are better than pills. Prozac was approved on the basis of two studies that found a positive result; it has since come out that there were three other trials that found it equal to placebo. Meta-analysis found antidepressants little better than placebo.
Things that you put on your head
- EEG feedback . Increase left frontal cortex activity and/or decrease right frontal cortex activity. Neurofeedback Treatment of Depression and Anxiety - review of various studies, showing pretty convincing evidence
- Transcranial magnetic stimulation . Repetitive stimulation to the dorsolateral prefrontal cortex. How could this be adapted to low-voltage systems like the Shakti?
- Direct current stimulation - This study found 10 sessions over 2 weeks of "anodal tDCS of the left dorsolateral prefrontal cortex" 4 times more effective than placebo. This study found improvements in suicide-risk hospitalized patients after 5 days of twice-daily treatment. Small meta-analysis supported efficacy. Gottta wonder about how lasting the effect is; I can't find a study with follow-up.
- I wonder if cathodal stimulation of the right dorsolateral prefrontal cortex has been tried? In theory, it should work.
Systems biology possibilities to be considered
- Vitamin D is needed to make serotonin and most people are deficient. Easily assessed by blood test.
- Hypothyroidism. One sampling found that 8% of depressed people have hypothyroidism, which is about twice the level in a normal population. Hypothyroidism leads to low levels of both serotonin and dopamine. Another study found that 13.6% of depressed people had subclinical hypothyroidism, and that that subset of depressed people are more panicky and less responsive to antidepressants. Lots of other studies confirm the link.
- Low testosterone - http://www.ncbi.nlm.nih.gov/pubmed/19625884 . This is tangled up with the Zn and Mg stuff mentioned above; deficiencies in these minerals will lead to low T and to depression. There are lots of good systems-biology ways of boosting T, including addressing these deficiencies 
- Inflammation - This paper is fascinating. Depressed people have higher inflammatory markers on average than the regular population (this says one-third of depressed people have elevated inflammatory markers), and medicines that cause inflammatory reacions have a well-known side-effect of depression, and elevated inflammatory markers predicts developing depression later. Interesting! This suggests that sombunall cases of depression could be treated by anti-inflammatory interventions. Intermittent fasting, eating less gluten, more herbs and spices, especially turmeric, more vegetables, less sugar etc.